Small molecules & peptides

PE2I

Reference standard for [¹¹C]PE2I

(E)-N-3-Iodoprop-2-enyl)-2β-carbomethoxy-3β-(p-tolyl)-nortropane

CA index name: 8-Azabicyclo[3.2.1]octane-2-carboxylic acid, 8-[(2E)-3-iodo-2-propenyl]-3-(4-methylphenyl)-, methyl ester, (1R,2S,3S,5S)-

Quality

Research Chemical

Characteristics

Molar mass 425.3

CAS RN [188680-71-9]

Purity ≥ 95 %

  • Colorless to yellowish solid

Certificates

CoA: appearance, ¹H NMR spectrum

Literature

Halldin C. et al. [¹¹C]PE2I: a highly selective radioligand for PET examination of the dopamine transporter in monkey and human brain. Eur. J. Nucl. Med. Mol. Imaging 2003, 30, 1220–1230.

Emond P. et al. Synthesis and Ligand Binding of Nortropane Derivatives: N-Substituted 2β-Carbomethoxy-3β-(4'-iodophenyl)-nortropane and N-(3-Iodoprop-(2E)-enyl)-2β-carbomethoxy-3β-(3',4'-disubstituted phenyl)nortropane. New High-Affinity and Selective Compounds for the Dopamine Transporter. J. Med. Chem. 1997, 40, 1366–1372.

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Product No.: 4170Filling amount: 10 mg
Product No.: 4170

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