Small molecules & peptides

(–)-McN 5652

Reference standard for (–)-[¹¹C]McN 5652

Pyrrolo[2,1-a]isoquinoline, 1,2,3,5,6,10b-hexahydro-6-[4-(methylthio)phenyl]-, (6R,10bS)-, (2S,3S)-2,3-di-(O-4-methylphenyloxy)butanedioate; (–)-McN 5652, (+)-di-O-toluyltartrate salt

CA index names: Butanedioic acid, 2,3-bis[(4-methylbenzoyl)oxy]-, (2S,3S)-, compd. with (6R,10bS)-1,2,3,5,6,10b-hexahydro-6-[4-(methylthio)phenyl]pyrrolo[2,1-a]isoquinoline (1:1); Pyrrolo[2,1-a]isoquinoline, 1,2,3,5,6,10b-hexahydro-6-[4-(methylthio)phenyl]-, (6R,10bS)-, (2S,3S)-2,3-bis[(4-methylbenzoyl)oxy]butanedioate (1:1)


Research Chemical


Molar mass 681.79

CAS RN [262352-33-0]

Purity ≥ 95 %

  • Colorless solid


CoA: appearance, ¹H and ¹³C NMR spectra

Product sheets (PDF)


Zessin J. et al. Efficient Synthesis of Enantiomerically Pure Thioester Precursors of [¹¹C]MCN-5652 from Racemic MCN-5652. J. Labelled Compd. Radiopharm. 1999, 42, 1301–12.

Parsey R.V. et al. In Vivo Quantification of Brain Serotonin Transporters in Humans Using [¹¹C]McN 565J. Nucl. Med. 2000, 41, 1465–1477.

Buck A. et al. Evaluation of Serotonergic Transporters Using PET and [¹¹C]McN 5652: Assessment of Methods. J. Cereb. Blood Flow Metab. 2000, 20, 253–262.

Suehiro M. et al. An improved method for the synthesis of radiolabeled McN5652 via thioester precursors. Nucl. Med. Biol. 1995, 22, 543–5.

Add to inquiry

Product No.Filling amountQuantity
Product No.: 4380Filling amount: 10 mg
Product No.: 4380
Product was added