Small molecules & peptides

(R)-(–)-Norapomorphine hydrobromide

Precursor for [¹¹C]-(–)-NPA and [¹¹C]-(–)-NMA ([¹¹C]-(–)-N-propyl-norapomorphine and [¹¹C]-(–)-N-methyl-norapomorphine)

4H-Dibenzo[de,g]quinoline-10,11-diol, 5,6,6a,7-tetrahydro-, hydrobromide, (R)-; (R)-(–)-Norapomorphine hydrobromide; (R)-(–)-Norapomorphine · HBr

CA index name: 4H-Dibenzo[de,g]quinoline-10,11-diol, 5,6,6a,7-tetrahydro-, hydrobromide, (6aR)-

Quality

Research Chemical

Characteristics

Molar mass 334.21

CAS RN [115017-61-3]

Purity ≥ 95 %

  • Colorless to yellowish solid

Certificates

CoA: appearance, ¹H NMR spectrum

Literature

Hwang D.-R. et al. (–)-N-[¹¹C]propyl-norapomorphine: a positron-labeled dopamine agonist for PET imaging of D2 receptors. Nucl. Med. Biol. 2000, 27, 533–539.

Narendran R. et al. In vivo vulnerability to competition by endogenous dopamine: Comparison of the D2 receptor agonist radiotracer (–)-N-[¹¹C]propyl-norapomorphine ([¹¹C]NPA) with the D2 receptor antagonist radiotracer [¹¹C]-raclopride. Synapse 2004, 52, 188–208.

Zijlstra S. et al. Synthesis and in vivo distribution in the rat of a dopamine agonist: N-([¹¹C]methyl)norapomorphine. Nucl. Med. Biol. 1993, 20, 7–12.

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