Small molecules & peptides
ABX474
Precursor for [99mTc]TcO-ABX474
ABX474
Sequence: Glu-CO-Lys-[(Sub)-DLys-Glu-Glu-BAT] (BAT: 5-((2-mercapto-2-methylpropyl)(2-((2-mercapto-2-methylpropyl)amino)ethyl)amino)pentanoic acid; Sub: suberic acid)
Quality
Research Chemical
Characteristics
Molar mass 1180.44 (net peptide)
CAS RN [not yet assigned]
Purity ≥ 95 %
- White to off-white solid
- soluble in water, methanol, dimethyl sulfoxide
Certificates
CoA: ESI-MS (identity), HPLC (purity)
Literature
Lis et al. Development of [99mTc]TcO-ABX474: Design, Synthesis, and Biological Evaluation of PSMA-Binding Technetium-99m Radioligands for SPECT Imaging of Prostate Cancer. Journal of Medicinal Chemistry 2025, https://doi.org/10.1021/acs.jmedchem.4c02767
Rahbar et al. First Experiences with the new 99mTc labelled PSMA ligand [99mTc]TcO-ABX474 in Patients with Advanced Prostate Cancer Prior to PSMA targeted Radioligand Therapy. Journal of Nuclear Medicine June 2024, 65 (supplement 2), 241711.
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| Product | Product No. | Filling amount | Quantity | ||
|---|---|---|---|---|---|
| /products/small-molecules-and-peptides/chemical/6bcf7927-387a-4a6f-be26-6c267cf64231 | Precursor | Product No.: 99470 |
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