Lu-DOTA-TOC
Reference standard for [¹⁷⁷Lu]Lu-DOTA-TOC
Lu-Edotreotide; Lu-SMT487; Lu-DOTA-[Tyr3]octreotide; Lutetium-175Lu, [N-[2-[4,7,10-tris[(carboxy-κO)methyl]-1,4,7,10-tetraazacyclododec-1-yl]acetyl-κO]-D-phenylalanyl-L-cysteinyl-L-tyrosyl-D-tryptophyl-L-lysyl-L-threonyl-N-[(1R,2R)-2-hydroxy-1-(hydroxymethyl)propyl]-L-cysteinamide cyclic(2→7)-disulfidato(3-)]-; Lutetium-175Lu, [N-[[4,7,10-tris[(carboxy-κO)methyl]-1,4,7,10-tetraazacyclododec-1-yl]acetyl-κO]-D-phenylalanyl-L-cysteinyl-L-tyrosyl-D-tryptophyl-L-lysyl-L-threonyl-N-[(1R,2R)-2-hydroxy-1-(hydroxymethyl)propyl]-L-cysteinamide cyclic(2→7)-disulfidato(3-)]-
Sequence: DOTA(Lu)-D-Phe-Cys-Tyr-D-Trp-Lys-Thr-Cys-Thr(ol), cyclic disulfide.
Quality
Research Chemical
Characteristics
Molar mass 1593.58 (Lu-DOTA-TOC)
CAS RN [321835-55-6] ([¹⁷⁷Lu]-DOTA-TOC)
Purity ≥ 95 %
- Colorless to off-white solid
Certificates
CoA: appearance, MS (identity), HPLC (purity)
Literature
Villard L. et al. Cohort study of somatostatin-based radiopeptide therapy with [⁹⁰Y-DOTA]-TOC versus [⁹⁰Y-DOTA]-TOC plus [¹⁷⁷Lu-DOTA]-TOC in neuroendocrine cancers. J. Clin. Oncol. 2012, 30, 1100–1106.
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Product | Product No. | Filling amount | Quantity | ||
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/products/small-molecules-and-peptides/chemical/6df2f0b7-118a-4b9a-b59f-036cb794ad60 | Reference Standard | Product No.: 9705 |