Small molecules & peptides
Desmethyl-MK-8278 (GMP)
Precursor for [¹¹C]MK-8278
trans-5'-Hydroxy-3'-oxo-N-methyl-N-(2-piperidin-1-ylethyl)-spiro[cyclohexane-1,1'-(3'H)-isobenzofuran]-4-carboxamide; [¹¹C]MK-8278 precursor
Spiro[cyclohexane-1,1'(3'H)-isobenzofuran]-4-carboxamide, 5'-hydroxy-N-methyl-3'-oxo-N-[2-(1-piperidinyl)ethyl]-, (1α,4β)-
Quality
GMP Product
Characteristics
Molar mass 386.48
CAS RN [879368-41-9]
Purity ≥ 97 %
- Colorless to off-white foam/solid
Certificates
CoA: appearance, ¹H NMR spectrum, HPLC
Literature
Van Laere K. J. et al. ¹¹C-MK-8278 PET as a Tool for Pharmacodynamic Brain Occupancy of Histamine 3 Receptor Inverse Agonists. J. Nucl. Med. 2014, 55, 65–72.
Hamill T. G. et al. Inverse Agonist Histamine H3 Receptor PET Tracers Labelled With Carbon-11 or Fluorine-18. Synapse 2009, 63, 1122–1132.
Add to inquiry
| Product | Product No. | Filling amount | Quantity | ||
|---|---|---|---|---|---|
| /products/small-molecules-and-peptides/chemical/71b7a1b4-40e8-4663-949e-0b5cea4a5630 | Precursor | Product No.: 3721 |
Related products
Product was added