Small molecules & peptides
DOTA-NOC acetate (GMP)
Precursor for radiolabelled DOTA-NOC
DOTA-[Nal3]-octreotide; CA index name: L-Cysteinamide, N-[[4,7,10-tris(carboxymethyl)-1,4,7,10-tetraazacyclododec-1-yl]acetyl]-D-phenylalanyl-L-cysteinyl-3-(1-naphthalenyl)- L-alanyl-D-tryptophyl-L-lysyl-L-threonyl-N-[(1R,2R)-2-hydroxy-1-(hydroxymethyl)propyl]-, cyclic (2→7)-disulfide
Sequence: DOTA-D-Phe-Cys-1Nal-D-Trp-Lys-Thr-Cys-Thr(ol), cyclic disulfide Cys2,7; DOTA = N-[[4,7,10-tris(carboxymethyl)-1,4,7,10-tetraazacyclododec-1-yl]acetyl]-; Nal = 3-(1-naphthalenyl )-L-alanyl; Supplied as acetate salt
Quality
GMP Product
Characteristics
Molar mass 1455.7
CAS RN [619300-53-7] (net peptide)
Purity ≥ 97 %
- Colorless to off-white solid
- Tested for bioburden and bacterial endotoxins.
Certificates
CoA: appearance, ESI-MS (identity), HPLC (purity), GC (residual solvents, acetate content, water content), heavy metal content (ICP-MS), microbiology test
Literature
Wild D. et al. ⁶⁸Ga-DOTANOC: a first compound for PET imaging with high affinity for somatostatin receptor subtypes 2 and 5. Eur. J. Nucl. Med. Mol. Imaging 2005, 32, 724.
Wild D. et al. DOTA-NOC, a high-affinity ligand of somatostatin receptor subtypes 2, 3 and 5 for labeling with various radiometals. Eur. J. Nucl. Med. Mol. Imaging 2003, 30, 1338–1347.
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| Product | Product No. | Filling amount | Quantity | ||
|---|---|---|---|---|---|
| /products/small-molecules-and-peptides/chemical/72c80589-1488-4803-9314-fe4a996f3e83 | Precursor | Product No.: 9716 | Filling amount: 50 µg | ||
| /products/small-molecules-and-peptides/chemical/72c80589-1488-4803-9314-fe4a996f3e83 | Precursor | Product No.: 9716 | Filling amount: 100 µg | ||
| /products/small-molecules-and-peptides/chemical/72c80589-1488-4803-9314-fe4a996f3e83 | Precursor | Product No.: 9716 | Filling amount: 250 µg | ||
| /products/small-molecules-and-peptides/chemical/72c80589-1488-4803-9314-fe4a996f3e83 | Precursor | Product No.: 9716 | Filling amount: 1000 µg | ||
| /products/small-molecules-and-peptides/chemical/72c80589-1488-4803-9314-fe4a996f3e83 | Precursor | Product No.: 9716 |
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