Small molecules & peptides

NITTP (GMP)

Precursor for [¹⁸F]FMISO ([¹⁸F]fluoromisonidazole)

1-(2'-Nitro-1'-imidazolyl)-2-O-tetrahydropyranyl-3-O-toluenesulfonyl-propanediol; 3-(2-Nitroimidazol-1-yl)-2-O-tetrahydropyranyl-1-O-toluenesulfonylpropanediol

CA index name: 1H-imidazole-1-propanol, 2-nitro-β-[(tetrahydro-2H-pyran-2-yl)oxy]-, 4-methylbenzenesulfonate (ester)

Quality

GMP Product

Characteristics

Molar mass 425.46

CAS RN [150196-34-2]

Purity ≥ 97 %

  • Yellowish solid

Certificates

CoA: appearance, NMR and IR spectra (identity), HPLC (purity), GC (residual solvents), microbiology test

Product sheets (PDF)

Literature

Oh S.J. et al. Fully automated synthesis of [¹⁸F]fluoromisonidazole using a conventional [¹⁸F]FDG module. Nucl. Med. Biol.2005, 32, 899–905.

Lim J.L. et al. An efficient radiosynthesis of [¹⁸F]Fluoromisonidazole. Appl. Radiat. Isot.1993, 44, 1085–1091.

Martin G.V. et al. Noninvasive detection of hypoxic myocardium using [¹⁸F]Fluoromisonidazole and positron emission tomography. J. Nucl. Med.1992, 33, 2202–2208.

Rasey J.S. et al. Radiolabeled fluoromisoindazole as an imaging agent for tumor hypoxia. Int. J. Radiat. Oncol. Biol. Phys. 1989, 17, 985–991.

Add to inquiry

Product No.Filling amountQuantity
Product No.: 1402Filling amount: 10 mg
Product No.: 1402

Related products

Product was added