Small molecules & peptides


Precursor for [¹⁸F]FMISO ([¹⁸F]fluoromisonidazole)

1-(2'-Nitro-1'-imidazolyl)-2-O-tetrahydropyranyl-3-O-toluenesulfonyl-propanediol; 3-(2-Nitroimidazol-1-yl)-2-O-tetrahydropyranyl-1-O-toluenesulfonylpropanediol

CA index name: 1H-imidazole-1-propanol, 2-nitro-β-[(tetrahydro-2H-pyran-2-yl)oxy]-, 4-methylbenzenesulfonate (ester)


GMP Product


Molar mass 425.46

CAS RN [150196-34-2]

Purity ≥ 97 %

  • Yellowish solid


CoA: appearance, NMR and IR spectra (identity), HPLC (purity), GC (residual solvents), microbiology test


Oh S.J. et al. Fully automated synthesis of [¹⁸F]fluoromisonidazole using a conventional [¹⁸F]FDG module. Nucl. Med. Biol.2005, 32, 899–905.

Lim J.L. et al. An efficient radiosynthesis of [¹⁸F]Fluoromisonidazole. Appl. Radiat. Isot.1993, 44, 1085–1091.

Martin G.V. et al. Noninvasive detection of hypoxic myocardium using [¹⁸F]Fluoromisonidazole and positron emission tomography. J. Nucl. Med.1992, 33, 2202–2208.

Rasey J.S. et al. Radiolabeled fluoromisoindazole as an imaging agent for tumor hypoxia. Int. J. Radiat. Oncol. Biol. Phys. 1989, 17, 985–991.

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Product No.: 1402Filling amount: 10 mg
Product No.: 1402

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