Small molecules & peptides

N-Boc-trans-4-tosyloxy-L-proline methyl ester

Precursor for cis-4-[¹⁸F]Fluoro-L-proline

N-tert-butyloxycarbonyl-O-p-toluenesulfonyl-L-proline methyl ester; N-tert-butyloxycarbonyl-trans-4-p-toluylsulfonyloxy-L-proline methyl ester; trans-BTPME

CA index name: 1,2-pyrrolidinedicarboxylic acid, 4-(((4-methylphenyl)-sulfonyl(oxyl(-1-(1,1-dimethylethyl)-2-methyl ester, (2S, trans)

Quality

Research Chemical

Characteristics

Molar mass 399.45

CAS RN [88043-21-4]

Purity ≥ 95 %

  • Colorless crystals

Certificates

CoA: appearance, ¹H NMR spectrum

Literature

Hamacher K. et al. [¹⁸F]fluoroproline: A potential tracer for collagen synthesis. Radiosynthesis and biological evaluation. 43rd Annual Meeting of the Society of Nuclear Medicine, Denver, Colorado, USA, June 3–5, 1996. J. Nucl. Med. 1996, 37, 41P.

Jones H. A. et al. External monitoring of ¹⁸F-fluoroproline uptake in a rabbit model of pulmonary fibrosis. Annual Congress of the European Respiratory Society, Berlin, Germany, September 20–24, 1977, European Respiratory Journal Supplement. 1977, 10, 323S-324S.

Gupta N.C. et al. Feasibility study for PET imaging of pulmonary fibrosis with cis-4-[¹⁸F]fluoro-L-proline (FP). J. Nucl. Med. 1998, 39, Proceedings of the 45th Annual Meeting, Toronto, Ontario, Canada P116-P117.

Mazza S.M. A Semi-Automatic Synthesis of cis-4-[¹⁸F]fluoro-L-proline using the General Electric FDG Microlab. J. Nucl. Med. 1998, 39, Proceedings of the 45th Annual Meeting, Toronto, Ontario, Canada P144.

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Product No.Filling amountQuantity
Product No.: 2300Filling amount: 16 mg
Product No.: 2300

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