Small molecules & peptides


Reference standard for 16α-[¹⁸F]Fluoroestradiol

16α-Fluoro-13β-methyl-1,3,5(10)-gonatriene-3,17β-diol; 16α-Fluoro-17β-estradiol; FES

CA index name: Estra-1,3,5(10)-triene-3,17-diol, 16-fluoro-, (16α,17β)-


Research Chemical


Molar mass 290.37

CAS RN [92817-10-2]

Purity ≥ 95 %

  • Colorless solid


CoA: appearance, ¹H and ¹⁹F NMR spectra


Mankoff D.A. et al. [¹⁸F]Fluoroestradiol Radiation Dosimetry in Human PET Studies. J. Nucl. Med. 2001, 42, 679–684.

Stalford A.C. et al. The metabolism of 16-fluoroestradiols in vivo: chemical strategies for restricting the oxidative biotransformations of an estrogen-receptor imaging agent. Steroids. 1997, 62, 750–761.

Roemer J. et al. Further 13C NMR spectroscopic proof of 16α-F configuration in 16-fluoroestradiol derivatives. Forschungszent. Rossendorf, [Ber.] FZR 1997, 165, 192–193.

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