(+)-McN 5652 Thiobutyrate
Precursor for (+)-[¹¹C]McN 5652
Thiobutyric acid (S)-[4-(1,2,3,5,6,10b-hexahydro-pyrrolo[2,1-a]isoquinolin-6-yl)-phenyl] ester; compound with 2,3-dihydroxy-succinic acid; S-Bu-McN-5652 tartrate
Butanethioic acid, (S)-[4-(1,2,3,5,6,10b-hexahydropyrrolo[2,1-a]isoquinolin-6-yl)phenyl] ester, trans-(+), (2R,3R)-2,3-dihydroxybutanedioate
Molar mass 501.59
CAS RN [167548-65-4] (free base)
Purity ≥ 95 %
CoA: appearance, ¹H NMR spectrum
Parsey R.V. et al. In Vivo Quantification of Brain Serotonin Transporters in Humans Using [¹¹C]McN 5652. J. Nucl. Med. 2000, 41, 1465–1477.
Buck A. et al. Evaluation of Serotonergic Transporters Using PET and [¹¹C]McN 5652: Assessment of Methods. J. Cereb. Blood Flow Metab. 2000, 20, 253–262.
Suehiro M. et al. An improved method for the synthesis of radiolabeled McN5652 via thioester precursors. Nucl. Med. Biol. 1995, 22, 543–545.