Small molecules & peptides


Complexation agent for [*Cu]-Labelling

Pyruvaldehyde bis(N⁴-methylthiosemicarbazone); Methylglyoxal bis-4-methylthiosemicarbazone

CA index names: Hydrazinecarbothioamide, 2,2'-(1-methyl-1,2-ethanediylidene)bis[N-methyl-; Pyruvaldehyde, bis(4-methyl-3-thiosemicarbazone); Semicarbazide, 1,1'-methylethanediylidene)bis[4-methyl-3-thio-


Research Chemical


Molar mass 246.36

CAS RN [673-68-7]

Purity ≥ 95 %

  • Colorless to yellowish solid


CoA: appearance, ¹H NMR spectrum


Green M.A. et al. Copper-62-Labeled Pyruvaldehyde Bis(N⁴-methylthiosemicarbazonato)copper(II): Synthesis and Evaluation as a Positron Emission Tomography Tracer for Cerebral and Myocardial Perfusion J. Nucl. Med. 1990, 31, 1989–1996.

Jalilian A. et al. Development of [¹⁰³Pd]-labeled-bis(N⁴-methylthiosemi-carbazone) complexes as possible therapeutic agents. Radiochim. Acta 2009, 94, 865–869.

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