Small molecules & peptides


Reference standard for [¹⁸F]NMB ([¹⁸F]-(3-N-methyl)benperidol)

1-[3-(4'-fluorobenzoyl)propyl]-4-(2-keto-3-methyl-1- benzimidazolinyl)piperidine); N-Methylbenperidol

CA index name: 2H-benzimidazol-2-one, 1-[1-[4-(4-Fluorophenyl)-4-oxobutyl]-4-piperidinyl]-1,3-dihydro-3-methyl-


Research Chemical


Molar mass 395.47

CAS RN [133066-70-3]

Purity ≥ 95 %

  • Colorless to brown powder


CoA: appearance, ¹H and ¹⁹F NMR spectra


Shiue C.-Y. et al. Syntheses and Specific Activity Determinations of No-Carrier-Added Fluorine-18-Labeled Neuroleptic Drugs J. Nucl. Med. 1985, 26, 181–186.

Suehiro M. et al. In Vivo Labeling of the Dopamine D2 Receptor with N-¹¹C-Methyl-Benperidol J. Nucl. Med. 1990, 31, 2015–2021.

Moerlein S.M. et al. Production of fluorine-18-labeled (3-N-methyl)benperidol for PET investigation of cerebral dopaminergic receptor binding. Int. J. Rad. Appl. Instrum. A 1992, 43, 913–917.

Moerlein S.M. et al. Radiation Dosimetry of [¹⁸F](N-Methyl)Benperidol as Determined by Whole-Body PET Imaging of Primates Nucl. Med. Biol. 1997, 24, 311–318.

Nikolaus S. et al. In Vivo Measurement of D2 Receptor Density and Affinity for ¹⁸F-(3-N-Methyl)Benperidol in the Rat Striatum with a PET System for Small Laboratory Animals J. Nucl. Med. 2003, 44, 618–624.

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Product No.: 2760Filling amount: 10 mg
Product No.: 2760

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