Small molecules & peptides

Copper tetraMIBI tetrafluoroborate (GMP)

Ligand for labelling with ⁹⁹mTc or ¹⁸⁸Re

Tetrakis (2-methoxy isobutyl isonitrile) Copper (I) tetrafluoroborate; Propane, 1-isocyano-2-methoxy-2-methyl-, copper complex; Cardio-Spect; [Cu(MIBI)₄]BF₄; Copper tetraMIBI tetrafluoroborate; CuMibi; Copper MIBI; Cu MIBI

CA index name: Copper(1+), tetrakis[1-(isocyano-κC)-2-methoxy-2-methylpropane]-, (T-4)-, tetrafluoroborate(1-)


GMP Product


Molar mass 602.98

CAS RN [103694-84-4]

Purity ≥ 99 %

  • Colorless to white crystalline solid


CoA: appearance, ¹H, ¹³C, ¹⁹F NMR, and IR spectra and melting point (identity), HPLC (purity), GC (residual solvents), Assay (HPLC), Assay Boron and Copper (ICP-MS), microbiology test


Taki J. et al. Assessment of P-glycoprotein in patients with malignant bone and soft-tissue tumors using technetium-99m-MIBI scintigraphy. J. Nucl. Med. 1998, 39, 1179–1184.

Kostakoglu L. et al. P-glycoprotein expression by technetium-99m-MIBI scintigraphy in hematologic malignancy. J. Nucl. Med. 1998, 39, 1191–1197.

Lee T.-W. et al. Synthesis, reactivity and 99mTc labeling of 2-alkoxyisobutylisonitrile. Appl. Radiat. Isot.1996, 47, 207–210.

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