Small molecules & peptides


Precursor for 6-O-[¹¹C]-buprenorphine


CA index name: 6,14-Ethenomorphinan-7-methanol, 17-(cyclporopyl-methyl)-α-(1,1-dimethylethyl)-4,5-epoxy-18,19-dihydro-6-hydroxy-α-methyl-3-(triphenylmethoxy)-, (5α, 7α(S))


Research Chemical


Molar mass 695.93

CAS RN [157891-93-5]

Purity ≥ 95 %

  • Colorless to yellowish solid


CoA: appearance, ¹H and ¹³C NMR spectra


Luthra S.K. et al. Automated radiosyntheses of [6-O-methyl-¹¹C]-diprenorphine and [6-O-methyl-¹¹C]buprenorphine from 3-O-trityl protected precursors. Appl. Radiat. Isot. 1994, 45, 857–873.

Luthra S.K. et al. Preparation of [¹¹C]buprenorphine - A potential radioligand for the study of the opiate receptor system in vivo. Int. J. Rad. Appl. Instrum. A. 1987, 38, 65–6.

Lever J.R. et al. Facile synthesis of [¹¹C]buprenorphine for positron emission tomographic studies of opioid receptors. J. Rad. Appl. Instrum. A, 1990, 41, 745–52.

Shiue C.Y. et al. A comparison of the brain uptake of N-(cyclopropyl[¹¹C]methyl)norbuprenorphine ([¹¹C]buprenorphine) and N-(cyclopropyl[¹¹C]methyl)nordiprenorphine ([¹¹C]diprenorphine) in baboon using PET. Int. J. Rad. Appl. Instrum. B, 1991, 18, 281–288.

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