Small molecules & peptides

TriBoc-L-DOPA ethyl ester (GMP)

Precursor for [¹⁸F]Fluoro-L-DOPA

N-(tert-butoxycarbonyl)-3,4-di(tert-butoxycarbonyloxy)-6-(trimethylstannyl)-L-phenylalanine ethyl ester

CA index name: L-Tyrosine, 5-[[(1,1-dimethylethoxy)carbonyl]oxy]-N-[(1,1-dimethylethoxy)carbonyl]-2-(trimethylstannyl)-, ethyl ester, 1,1-dimethylethyl carbonate

Quality

GMP Product

Characteristics

Molar mass 688.39

CAS RN [203398-46-3]

Purity ≥ 97 %

  • Colorless solid

Certificates

CoA: appearance, NMR spectra and optical rotation (identity), HPLC (purity), GC (residual solvents), ICP-MS (inorganic impurities)

Literature

Dollé F. et al. 6-[¹⁸F]Fluoro-L-DOPA by Radiofluorodestannylation: A Short and Simple Synthesis of a New Labelling Precursor. J. Labelled Compd. Radiopharm. 1998, 41, 105–114.

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