Small molecules & peptides

Ethyl 4-nitrobenzoate

Precursor for [¹⁸F]FB (4-[¹⁸F]fluorobenzoic acid)

4-(Ethoxycarbonyl)nitrobenzene; 4-Ethoxycarbonyl-1-nitrobenzene; 4-Nitrobenzoic acid ethyl ester; [18F]FB precursor

Ethyl 4-nitrobenzoate


Research Chemical


Molar mass 195.17

CAS RN [99-77-4]

Purity ≥ 95 %

  • Colorless to off-white solid
  • soluble in ethyl acetate, chloroform, dichloromethane


CoA: appearance, ¹H NMR spectrum


Reed C. D. et al. Evaluation of tetraethylammonium bicarbonate as a phase-transfer agent in the formation of [¹⁸F]fluoroarenes. J. Fluor. Chem. 2012, 143, 231–237.

Moore T. M. et al. A rapid microfluidic synthesis of [¹⁸F]fluoroarenes from nitroarenes. Appl. Radiat. Isot. 2013, 71, 47–50.

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