Small molecules & peptides
THK-5351 precursor
Precursor for synthesis of [18F]THK-5351
THK-5352; THK-5152S
(2S)-3-((2-(6-(methylamino)pyridin-3-yl)quinolin-6-yl)oxy)-2-((tetrahydro-2H-pyran-2-yl)oxy)propyl 4-methylbenzenesulfonate
Quality
Research Chemical
Characteristics
Molar mass 563.67
CAS RN [1707147-35-0]
Purity ≥ 95 %
- white to off-white solid
- soluble in chloroform, acetonitrile, dimethyl sulfoxide
Certificates
CoA: appearance, 1H NMR spectrum (identity), HPLC (purity)
Literature
Betthauser, T.J. et al. Characterization of the radiosynthesis and purification of [18F]THK-5351, a PET ligand for neurofibrillary tau. Appl. Radiat. Isot. 2017, 130, 230–237.
Harada, R. et al.18F-THK5351: A Novel PET Radiotracer for Imaging Neurofibrillary Pathology in Alzheimer Disease. J. Nucl. Med. 2016, 57, 208−214.
Harada, R. et al. Correlations of 18F-THK5351 PET with Postmortem Burden of Tau and Astrogliosis in Alzheimer Disease. J. Nucl. Med. 2018, 59, 671−674.
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| Product | Product No. | Filling amount | Quantity | ||
|---|---|---|---|---|---|
| /products/small-molecules-and-peptides/chemical/af3c4ecc-8249-4c4d-a01a-8dde1a9ee425 | Precursor | Product No.: 5198 |
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