Small molecules & peptides

TATE

Reference standard for impurity of DOTA-TATE acetate

[Tyr3]Octreotate trifluoracetate; TOCA; CA index name: L-Threonine, D-phenylalanyl-L-cysteinyl-L-tyrosyl-D-tryptophyl-L-lysyl-L-threonyl-L-cysteinyl-, cyclic (2→7)-disulfide,

Sequence: H-D-Phe-Cys-Tyr-D-Trp-Lys-Thr-Cys-Thr-OH, cyclic disulfide

Quality

Research Chemical

Characteristics

Molar mass 1049.22

CAS RN [302794-43-0] (net peptide)

Purity ≥ 95 %

  • Colorless freeze-dried solid

Certificates

CoA: appearance, MS (identity), HPLC (purity)

Literature

Petrou C. et al. Synthesis and sst2 binding profiles of new (Tyr3)octreotate analogs. J.Peptide Sci. 2008, 14, 725–730.

Spyroulias G.A. et al. 3D solution structure of [Tyr3]octreotate derivatives in DMSO: Structure differentiation of peptide core due to chelate group attachment and biologically active conformation. Med. Chem. 2005, 1, 487–499.

Wang Q. et al. Pharmacological properties of hydrophilic and lipophilic derivatives of octreotate. Nucl. Med. Biol. 2004, 31, 21–30.

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