Benzyl-14-(R,S)-tosyloxy-6-thiaheptadecanoate
Precursor for [¹⁸F]FTHA (14-(R,S)-[¹⁸F]fluoro-6-thia-heptadecanoic acid)
14-(R,S)-Tosyloxy-6-thiaheptadecanoic acid benzyl ester; Tos-THA
CA index name: Pentanoic acid, 5-[[8-[[(4-methylphenyl)sulfonyl]oxy]undecyl]thio]-phenylmethyl ester ±
Quality
Research Chemical
Characteristics
Molar mass 548.79
CAS RN [137564-70-6]
Purity ≥ 95 %
- Yellowish oil
- soluble in dimethyl sulfoxide, ethanol, methanol, dimethylformamide, chloroform
Certificates
CoA: appearance, ¹H and ¹³C NMR spectra, water content
Literature
DeGrado T.R. et al. Synthesis of 14-(R,S)-[¹⁸F]fluoro-6-thia-heptadecanoic acid. J. Labelled Compd. Radiopharm. 1991, 29, 989–995.
DeGrado T.R. et al. 14(R,S)-[¹⁸F]fluoro-6-thia-heptadecanoic acid (FTHA): evaluation in mouse of a new probe of myocardial utilization of a long chain fatty acids. J. Nucl. Med. 1991, 32, 1888–1896.
Maeki M.T. et al. Free Fatty Acid Uptake in the Myocardium and Skeletal Muscle Using Fluorine-18-Fluoro-6-Thiaheptadecanoic Acid. J. Nucl. Med. 1998, 39, 1320–1327.
Taylor M. et al. An Evaluation of Myocardial Fatty Acid and Glucose Uptake Using PET with [¹⁸F]Fluoro-6-Thia-Heptadecanoic Acid and [¹⁸F]FDG in Patients with Congestive Heart Failure. J. Nucl. Med. 2001, 42, 55–62.
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Product | Product No. | Filling amount | Quantity | ||
---|---|---|---|---|---|
/products/small-molecules-and-peptides/chemical/cca92c6c-6ab3-411a-9502-fb510f538829 | Precursor | Product No.: 2850 | Filling amount: 10 mg | ||
/products/small-molecules-and-peptides/chemical/cca92c6c-6ab3-411a-9502-fb510f538829 | Precursor | Product No.: 2850 |