Small molecules & peptides

Benzyl-14-(R,S)-tosyloxy-6-thiaheptadecanoate

Precursor for [¹⁸F]FTHA (14-(R,S)-[¹⁸F]fluoro-6-thia-heptadecanoic acid)

14-(R,S)-Tosyloxy-6-thiaheptadecanoic acid benzyl ester; Tos-THA

CA index name: Pentanoic acid, 5-[[8-[[(4-methylphenyl)sulfonyl]oxy]undecyl]thio]-phenylmethyl ester ±

Quality

Research Chemical

Characteristics

Molar mass 548.79

CAS RN [137564-70-6]

Purity ≥ 95 %

  • Yellowish oil
  • soluble in dimethyl sulfoxide, ethanol, methanol, dimethylformamide, chloroform

Certificates

CoA: appearance, ¹H and ¹³C NMR spectra, water content

Literature

DeGrado T.R. et al. Synthesis of 14-(R,S)-[¹⁸F]fluoro-6-thia-heptadecanoic acid. J. Labelled Compd. Radiopharm. 1991, 29, 989–995.

DeGrado T.R. et al. 14(R,S)-[¹⁸F]fluoro-6-thia-heptadecanoic acid (FTHA): evaluation in mouse of a new probe of myocardial utilization of a long chain fatty acids. J. Nucl. Med. 1991, 32, 1888–1896.

Maeki M.T. et al. Free Fatty Acid Uptake in the Myocardium and Skeletal Muscle Using Fluorine-18-Fluoro-6-Thiaheptadecanoic Acid. J. Nucl. Med. 1998, 39, 1320–1327.

Taylor M. et al. An Evaluation of Myocardial Fatty Acid and Glucose Uptake Using PET with [¹⁸F]Fluoro-6-Thia-Heptadecanoic Acid and [¹⁸F]FDG in Patients with Congestive Heart Failure. J. Nucl. Med. 2001, 42, 55–62.

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Product No.Filling amountQuantity
Product No.: 2850Filling amount: 10 mg
Product No.: 2850

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