Small molecules & peptides

(–)-Flubatine precursor

Precursor for (–)-[¹⁸F]Flubatine

ABX075; (–)-Flubatine precursor; (–)-NCFHEB precursor; (–)-5-(8-tert-butoxycarbonyl)-8-azabicyclo[3.2.1]octan-6-yl)-N,N,N-trimethylpyridin-2-aminium iodide

5-((1R, 5S, 6S)-8-tert-butoxycarbonyl)-8-azabicyclo[3.2.1]octan-6-yl)-N,N,N-trimethylpyridin-2-aminium iodide


Research Chemical


Molar mass 473.39

CAS RN [1421915-93-6]

Purity ≥ 95 %

  • White to yellowish solid


CoA: appearance, ¹H NMR spectrum, HPLC


Präkursorverbindungen für die Radiosynthese von [¹⁸F]Norchlor-fluor-homoepibatidin. Patent DE 2011080118062700

Brust P. et al. In vivo measurement of nicotinic acetylcholine receptors with [¹⁸F]norchloro-fluoro-homoepibatidine. Synapse 2008, 62, 205–218.

Deuther-Conrad W. et al. Norchloro-fluoro-homoepibatidine (NCFHEB) - a promising radioligand for neuroimaging nicotinic acetylcholine receptors with PET. Eur. Neuropsychopharmacol. 2008, 18, 222–229.

Deuther-Conrad W. et al. Norchloro-fluoro-homoepibatidine: specificity to neuronal nicotinic acetylcholine receptor subtypes in vitro. Farmaco, 2004, 59, 785–792.

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