Reference standard for [¹⁸F]FDG synthesis (2-[¹⁸F]fluoro-2-deoxy-D-glucose)
2-Deoxy-2-fluoro-D-glucose; 2-Deoxy-fluoro-glucose; Fludeoxyglucose
CA index name: D-Glucopyranose, 2-deoxy-2-fluoro-
Molar mass 182.15
CAS RN [86783-82-6] (pyranoside); [29702-43-0] (aldehyde)
Purity ≥ 95 %
CoA: appearance, ¹H and ¹⁹F NMR spectra
Hamacher K. et al. Efficient stereospecific synthesis of no-carrier-added 2-[¹⁸F]fluoro-2-deoxy-D-glucose using aminopolyether supported nucleophilic substitution. J. Nucl. Med. 1986, 27, 235–238.
Padgett H.C. et al. Computer-controlled radiochemical synthesis: a chemistry process control unit for the automated production of radiochemicals. Appl. Radiat. Isot. 1989, 40, 433–445.
Tóth G. et al. Synthesis of 2-deoxy-2-[¹⁸F]Fluoro-D-glucose and its precursors for human diagnostics. Izotóptechnika, Diagnosztika 1992, 35, 65–72.
Füchtner F. et al. Basic Hydrolysis of 2-[¹⁸F]Fluoro-1,3,4,6-tetra-O-acetyl-D-glucose in the Preparation of 2-[¹⁸F]Fluoro-D-glucose. Appl. Radiat. Isot. 1996, 47, 61–66.
Mannose Triflate plus, ultra pure
[¹⁸F]FDG − multiple runs