Small molecules & peptides


Reference standard for [¹⁸F]FDG synthesis (2-[¹⁸F]fluoro-2-deoxy-D-glucose)

2-Deoxy-2-fluoro-D-glucose; 2-Deoxy-fluoro-glucose; Fludeoxyglucose

CA index name: D-Glucopyranose, 2-deoxy-2-fluoro-


Research Chemical


Molar mass 182.15

CAS RN [86783-82-6] (pyranoside); [29702-43-0] (aldehyde)

Purity ≥ 95 %

  • Colorless to off-wite solid
  • soluble in methanol, dimethyl sulfoxide, water


CoA: appearance, ¹H and ¹⁹F NMR spectra


Hamacher K. et al. Efficient stereospecific synthesis of no-carrier-added 2-[¹⁸F]fluoro-2-deoxy-D-glucose using aminopolyether supported nucleophilic substitution. J. Nucl. Med. 1986, 27, 235–238.

Padgett H.C. et al. Computer-controlled radiochemical synthesis: a chemistry process control unit for the automated production of radiochemicals. Appl. Radiat. Isot. 1989, 40, 433–445.

Tóth G. et al. Synthesis of 2-deoxy-2-[¹⁸F]Fluoro-D-glucose and its precursors for human diagnostics. Izotóptechnika, Diagnosztika 1992, 35, 65–72.

Füchtner F. et al. Basic Hydrolysis of 2-[¹⁸F]Fluoro-1,3,4,6-tetra-O-acetyl-D-glucose in the Preparation of 2-[¹⁸F]Fluoro-D-glucose. Appl. Radiat. Isot. 1996, 47, 61–66.

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