Precursor for [¹⁸F]-labelled building block for different alkylbenzenes (fluorine-18-labelled haloperidol, spiperone, N-(p-nitrobenzyl)spiperone, N-methyl-spiroperidol, BMY14802, 3-N-methyl-benperidol, benperidol)
CA index name: Methanone, cyclopropyl-(4-nitrophenyl)-
Hashizume K. et al. Rapid and efficient synthesis of high-purity fluorine-18 labeled haloperidol and spiperone via the nitro precursor in combination with a new HPLC separation method. Bull. Chem. Soc. Jpn.1997, 70, 681–687.
Mach R. H. et al. Synthesis and in vivo evaluation of [¹⁸F]-N-(p-nitrobenzyl)spiperone ([¹⁸F]PNBS) in rats. Nucl. Med. Biol.1993, 20, 269–278.
Moerlein S.M. et al. Production of fluorine-18-labeled (3-N-methyl)benperidol for PET investigation of cerebral dopaminergic receptor binding. Int. J. Rad. Appl. Instrum. A1992, 43, 913–917.
Shiue C.Y. et al. Synthesis of (±)-[¹⁸F]BMY14802, its enantiomers and their anatomical distribution in mice. Nucl. Med. Biol.1993, 20, 625–630.