Small molecules & peptides

T807 precursor

Precursor for [18F]T807

5H-Pyrido[4,3-b]indole-5-carboxylic acid, 7-(6-nitro-3-pyridinyl)-, 1,1-dimethylethyl ester (ACI); [18F]T807 precursor

tert-butyl 7-(6-nitropyridin-3-yl)-5H-pyrido[4,3-b]indole-5-carboxylate

Quality

Research Chemical

Characteristics

Molar mass 390.40

CAS RN [1533432-50-6]

Purity ≥95%

  • yellow solid
  • soluble in DMSO and chloroform

Certificates

1H-NMR (identity), HPLC (purity)

Literature

Gao M. et al. Fully automated synthesis of [18F]T807, a PET tau tracer for Alzheimer’s disease. Med. Chem. Lett. 2015, 25, 2953–2957.

Shoup, T.M. et al. A concise radiosynthesis of the tau radiopharmaceutical, [18F]T807. J. Labelled Comp. Rad, 2013, 56, 736-740.

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