Small molecules & peptides

AFM standard

Reference standard for [¹¹C]AFM and [¹⁸F]AFM ([¹¹C]2-(2-(dimethylaminomethyl)phenylthio)-5-fluoromethylphenylamine)

2-(2-Dimethylaminomethyl-phenylsulfanyl)-5-fluoromethyl-phenylamine hydrochloride salt

Benzenemethanamine, 2-[[2-amino-4-(fluoromethyl)phenyl]thio]-N,N-dimethyl-, hydrochloride salt


Research Chemical


Molar mass 290.40 (free base)

CAS RN [627490-40-8] (free base)

Purity ≥ 90 %

  • Colorless solid


CoA: appearance, ¹H and ¹⁹F NMR spectra


Huang Y. et al. Comparative Evaluation in Nonhuman Primates of Five PET Radiotracers for Imaging the Serotonin Transporters: [¹¹C]McN 5652, [¹¹C]ADAM, [¹¹C]DASB, [¹¹C]DAPA, and [¹¹C]AFM. J. Cereb. Blood Flow Metab. 2002, 22, 1377–1398.

Huang Y. et al. Fluorinated Analogues of ADAM as New PET Radioligands for the Serotonin Transporter : Synthesis and Pharmacological Evaluation. J. Labelled Compd. Radiopharm. 2001, 44, Suppl. 1, S18-S20.

Oya S. et al. New PET Imaging Agent for the Serotonin Transporter: [¹⁸F]ACF (2-[(2-Amino-4-chloro-5-fluorophenyl)thio]-N,N-dimethyl-benzenemethanamine). J. Med. Chem. 2002, 45, 4716–23.

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Product No.: 4330Filling amount: 10 mg
Product No.: 4330

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