Small molecules & peptides
PSMA-1007 reference standard
Reference Standard for [¹⁸F]PSMA-1007
[¹⁸F]PSMA-1007 standard
(3S,10S,14S)-1-(4-(((S)-4-carboxy-2-((S)-4-carboxy-2-(6-fluoronicotinamido)butanamido)butanamido)methyl)phenyl)-3-(naphthalen-2-ylmethyl)-1,4,12-trioxo-2,5,11,13-tetraazahexadecane-10,14,16-tricarboxylic acid
Quality
Research Chemical
Characteristics
Molar mass 1031.00
CAS RN [not yet assigned]
Purity ≥ 95 %
- colorless to off-white solid
- soluble in dimethyl sulfoxide
Certificates
CoA: appearance, ¹H NMR and ¹⁹F NMR spectra (identity), HPLC (purity)
Literature
Giesel F.L. et al. ¹⁸F-PSMA-1007 PET/CT Detects Micrometastases in a Patient With Biochemically Recurrent Prostate Cancer. Clin. Genitourin. Cancer. 2016. doi: 10.1016/j.clgc.2016.12.029.
Giesel F.L. et al. F-18 labelled PSMA-1007: biodistribution, radiation dosimetry and histopathological validation of tumor lesions in prostate cancer patients. Eur. J. Nucl. Med. Mol. Imaging 2017, 44(4), 678–688. doi: 10.1007/s00259-016–3573–4.
Cardinale J. et al. Preclinical Evaluation of [¹⁸F]PSMA-1007: A New PSMA-Ligand for Prostate Cancer Imaging. J. Nucl. Med. 2016. doi: 10.2967/jnumed.116.181768
Giesel F.L. et al. ¹⁸F-Labelled PSMA-1007 shows similarity in structure, biodistribution and tumour uptake to the theragnostic compound PSMA-617. Eur. J. Nucl. Med. Biol. 2016, 43, 1929–30.
Kesch C. et al. Intra-individual comparison of ¹⁸F-PSMA-1007-PET/CT, multi-parametric MRI and radical prostatectomy specimen in patients with primary prostate cancer - a retrospective, proof of concept study. J Nucl Med. 2017 doi: 10.2967/jnumed.116.18933
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| Product | Product No. | Filling amount | Quantity | ||
|---|---|---|---|---|---|
| /products/small-molecules-and-peptides/chemical/7e8da41f-8d5d-44f8-bbee-949823042c68 | Reference Standard | Product No.: 99433 | Filling amount: 5 mg | ||
| /products/small-molecules-and-peptides/chemical/7e8da41f-8d5d-44f8-bbee-949823042c68 | Reference Standard | Product No.: 99433 | Filling amount: 10 mg | ||
| /products/small-molecules-and-peptides/chemical/7e8da41f-8d5d-44f8-bbee-949823042c68 | Reference Standard | Product No.: 99433 |
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