Small molecules & peptides

6-Fluoro-L-DOPA hydrochloride

Reference standard for 6-[¹⁸F]Fluoro-L-DOPA

2-Fluoro-5-hydroxyl-L-tyrosine hydrochloride; 6-Fluoro-L-DOPA hydrochloride; 6-Fluoro-DOPA-hydrochloride; F-L-DOPA · HCl; FDOPA

CA index name: L-Tyrosine, 2-fluoro-5-hydroxy-, hydrochloride


Research Chemical


Molar mass 251.64

CAS RN [144334-59-8]

Purity ≥ 95 %

  • Nearly colorless solid


CoA: appearance, ¹H and ¹⁹F NMR spectra, HPLC


Namavari M. et al. Regioselective Radiofluorodestannylation with [¹⁸F]CH₃COOF: a High Yield Synthesis of 6-[¹⁸F]Fluoro-L-dopa. Appl. Radiot. Isot., Int. J. Radiat. Appl. Instrum. Part A 1992, 43, 989–996.

Iwata R. et al. Regioselective Synthesis of 6-[¹⁸F]-Fluoro-L-dopa via Radiofluorodestannylation. CYRIC Annual Report, 1997, 99–102.

Dollé F. et al. 6-[¹⁸F]Fluoro L DOPA by Radiofluorodestannylation: A Short and Simple Synthesis of a New Labelling Precursor. J. Labelled Compd. Radiopharm. 1998, 41, 105–114.

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