Phd position (m/f/d)
Our profile
ABX is a young, fast-growing chemical and pharmaceutical company based in Saxony, Germany. We are the global market leader in the production of precursors and kits for PET diagnostics. These are mainly used in the detection of tumours by positron emission tomography (PET).ABX currently employs around 400 people. Due to our strong market position we have a continuous profitable growth. Since 2007 we have been part of a large Japanese pharmaceutical group.We are pleased to offer you the opportunity of a doctoral position starting September 1st.
The position is part of the Doctoral Network (DN) “WATER”, which aims to train 16 PhD students to unravel the multiple roles of interfacial water in biological membranes. The network will be funded under the Marie Skłodowska-Curie Actions (MSCA).
Research project: Development of strategies to protect salivary glands from radiation caused by radioligand therapy (RLT)
The project aims to minimize the negative side effects of radioligands on salivary glands, either by (i) blocking the binding of PSMA targeting drugs in the vicinity of gland aquaporins during radiation therapy with compounds that occupy these binding sites (e.g. bind to aquaporins or their interaction partners), (ii) equipping radioprotectors which have radical-scavenging properties with moieties that recognise aquaporins or their interaction partners, or (iii) developing PSMA- and/or GCPII-ligands with photocleavable linkers.Required qualifications
We are looking for students who hold or are very close to completing their MSc degree in biophysics, physics, biochemistry, biomedical sciences, pharmacy, biology, chemistry, bioinformatics, biomedical engineering, chemical engineering or equivalent degree. We particularly value:- Academic engagement and achievement, e.g., demonstrated through coursework, research experience, awards, scholarships, etc.
- A growth mindset, problem-solving skills, analytical and independent thinking
- Communication, presentation, and teamwork skills
- Competence in written and spoken English
- Applicants must not have resided or carried out their main activity (work, studies, etc.) in the recruiting institution's country for more than 12 months in the three years immediately before the recruitment date, excluding short stays such as holidays or compulsory national service
- Profound knowledge of organic chemistry and hands-on experience in organic synthesis (planning and carrying out multi-step syntheses, including compound purification and characterization of reaction products
- Experience in the interpretation of analytical data (NMR, HPLC, LC-MS)
- Preferentially, experience of or keen interest in medicinal chemistry, drug design, chemical biology or related fields
- Proficient in searching the chemical literature
- High level of motivation, curiosity and initiative
- Strong problem-solving abilities, including critical thinking skills and attention to detail and Basic knowledge of the German language or willingness to learn it is desirable
If you are interested, we look forward to receiving your application documents by e-mail in pdf format.
The application should include motivation letter, curriculum vitae, contact data of two reference persons who are willing to write a letter of recommendation upon request, copies of Bachelor and Master Certificates (or transcript of grades achieved so far if the final master certificate is not yet issued) with marks, and publications and/or contributions to conferences (if any) and should be sent to ABX and water@jku.at .
Dr. Christian Lis will be happy to answer any technical questions you may have, and Ms. Conny Kobus will be happy to answer any questions about the application process.
Contact
ABX advanced biochemical compounds -Biomedizinische Forschungsreagenzien GmbH
Heinrich-Gläser-Straße 10-14
01454 Radeberg
Tel.-Nr.: +49 3528 40 41 66
E-Mail: bewerbungen@abx.de
Homepage: www.abx.de