Small molecules & peptides

GR 205171

Reference standard for [¹¹C]GR 205171

3-Piperidinamine, N-[[2-methoxy-5-[5-(trifluormethyl)-1H-tetrazol-1-yl]phenyl]methyl]-2-phenyl, (2S-cis-); Vofopitant

CA index name: 3-Piperidinamine, N-[[2-methoxy-5-[5-(trifluormethyl)-1H-tetrazol-1-yl]phenyl]methyl]-2-phenyl, (2S,3S)


Research Chemical


Molar mass 432.44

CAS RN [168266-90-8]

Purity ≥ 95 %

  • Yellowish solid


CoA: appearance, ¹H, ¹³C and ¹⁹F NMR spectra


Bergström M. et al. Brain uptake and receptor binding of two [¹¹C]labelled selective high affinity NK1-antagonists, GR203040 and GR205171-PET studies in rhesus monkey. Neuropharmacology 2000, 39, 664–670.

Zamuner S. et al. Estimate the time varying brain receptor occupancy in PET imaging experiments using non-linear fixed and mixed effect modeling approach Nucl. Med. Biol. 2002, 29, 115–123.

Bergström M. et al. A new application of pre-normalized principal component analysis for improvement of image quality and clinical diagnosis in human brain PET studies--clinical brain studies using [¹¹C]-GR205171, [¹¹C]-L-deuterium-deprenyl, [¹¹C]-5-Hydroxy-L-Tryptophan, [¹¹C]-L-DOPA and Pittsburgh Compound-B. Neuroimage 2006, 33, 588–598.

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