Small molecules & peptides
GR 205171 Dihydrochloride
Reference standard for [¹¹C]GR 205171
3-Piperidinamine, N-[[2-methoxy-5-[5-(trifluoromethyl)-1H-tetrazol-1-yl]phenyl]methyl]-2-phenyl-, dihydrochloride, (2S-cis)-; GR 205171A; Vofopitant dihydrochloride
CA index name: 3-Piperidinamine, N-[[2-methoxy-5-[5-(trifluoro-methyl)-1H-tetrazol-1-yl]phenyl]methyl]-2-phenyl-, dihydrochloride, (2S,3S)-
Quality
Research Chemical
Characteristics
Molar mass 505.36
CAS RN [168266-51-1]
Purity ≥ 95 %
- Off-white to yellowish solid
Certificates
CoA: appearance, ¹H, ¹³C and ¹⁹F NMR spectra
Literature
Bergström M. et al. Brain uptake and receptor binding of two [¹¹C]labelled selective high affinity NK1-antagonists, GR203040 and GR205171-PET studies in rhesus monkey. Neuropharmacology 2000, 39, 664–670.
Zamuner S. et al. Estimate the time varying brain receptor occupancy in PET imaging experiments using non-linear fixed and mixed effect modeling approach Nucl. Med. Biol. 2002, 29, 115–123.
Bergström M. et al. A new application of pre-normalized principal component analysis for improvement of image quality and clinical diagnosis in human brain PET studies--clinical brain studies using [¹¹C]-GR205171, [¹¹C]-L-deuterium-deprenyl, [¹¹C]-5-Hydroxy-L-Tryptophan, [¹¹C]-L-DOPA and Pittsburgh Compound-B. Neuroimage 2006, 33, 588–598.
Add to inquiry
| Product | Product No. | Filling amount | Quantity | ||
|---|---|---|---|---|---|
| /products/small-molecules-and-peptides/chemical/dbd33e6a-2bd2-4e19-9c8f-de6bcc4a75b3 | Reference Standard | Product No.: 3530 | Filling amount: 10 mg | ||
| /products/small-molecules-and-peptides/chemical/dbd33e6a-2bd2-4e19-9c8f-de6bcc4a75b3 | Reference Standard | Product No.: 3530 |
Related products
Product was added