Small molecules & peptides


Reference standard for [¹⁸F]CPFPX (8-cyclopentyl-3-(3-[¹⁸F]fluoropropyl)-1-propylxanthine)

8-Cyclopentyl-3-(3-fluoro-propyl)-1-propyl-3,7-dihydro-purine-2,6-dione; 8-Cyclopentyl-3-(3-[¹⁸F]fluoropropyl)-1-propylxanthine

CA index name: 1H-Purine-2,6-dione, 8-cyclopentyl-3-(3-fluoropropyl)-3,9-dihydro-1-propyl-


Research Chemical


Molar mass 322.38

CAS RN [200557-18-2]

Purity ≥ 95 %

  • Colorless to off-white solid


CoA: appearance, ¹H and ¹⁹F NMR spectra


Holschbach M. H. et al. Synthesis and Evaluation of No-Carrier-Added 8-Cyclopentyl-3-(3-[¹⁸F]fluoropropyl)-1-propylxanthine ([¹⁸F]CPFPX): A Potent and Selective A1-Adenosine Receptor Antagonist for in Vivo Imaging. J. Med. Chem. 2002, 45, 5150–5156.

Bauer A. et al. Evaluation of ¹⁸F-CPFPX, a Novel Adenosine A1 Receptor Ligand: In Vitro Autoradiography and High-Resolution Small Animal PET. J. Nucl. Med. 2003, 44, 1682–1689.

Matusch A. et al. Metabolism of the A1 adenosine receptor PET ligand [¹⁸F]CPFPX by CYP1A2: implications for bolus/infusion PET studies. Nucl. Med. Biol. 2006, 33, 891–898.

Elmenhorst D. et al. Caffeine Occupancy of Human Cerebral A1 Adenosine Receptors: In Vivo Quantification with ¹⁸F-CPFPX and PET. J. Nucl. Med. 2012, 53, 1723–1729.

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Product No.: 3751Filling amount: 10 mg
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