Small molecules & peptides


Precursor for [¹⁸F]FAP

2-Nitro-AP; 2-Nitro-A85380; 2-Nitro-3-[2(S)-N-tert-butoxycarbonyl]-[(2-azetidinyl)-methoxy]pyridine

CA index name: 1-Azetidinecarboxylic acid, 2-[[[2-nitro-3-pyridinyl]oxy]methyl]-, 1,1-dimethylethyl ester, (2S)-


Research Chemical


Molar mass 309.32

CAS RN [209530-92-7]

Purity ≥ 95 %

  • Yellowish solid


CoA: appearance, ¹H NMR spectrum


Dollé F. et al. Synthesis of 2-[¹⁸F]Fluoro-3-[2(S)-2-azetidinyl-methoxy]pyridine, a highly potent radioligand for in vivo imaging central nicotinic acetylcholine receptors. J. Labelled Compd. Radiopharm. 1998, 41, 451–463.

Dollé F. et al. Synthesis and Nicotinic Acetylcholine Receptor in Vivo Binding Properties of 2-Fluoro-3-[2(S)-2-azetidinylmethoxy]-pyridine: A New Positron Emission Tomography Ligand for Nicotinic Receptors. J. Med. Chem. 1999, 42, 2251–2259.

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