Small molecules & peptides


Precursor for [¹⁸F]FAP

2-TMAAP; 2-TMA-A85380; (3-[2(S)-N-(tert-butoxycarbonyl)-2-azetidinyl-methoxy]pyridin-2-yl)-trimethylammonium trifluoromethanesulfonate

CA index name: 2-Pyridinaminium, 3-[[(2S)-1-[(1,1-dimethylethoxy)carbonyl]-2-azetidinyl]methoxy]-N,N,N-trimethyl-, salt with trifluoromethanesulfonic acid (1:1)


Research Chemical


Molar mass 471.49

CAS RN [233766-75-1]

Purity ≥ 95 %

  • Colorless solid


CoA: appearance, ¹H and ¹⁹F NMR spectra


Dollé F. et al. Synthesis and Nicotinic Acetylcholine Receptor in Vivo Binding Properties of 2-Fluoro-3-[2(S)-2-azetidinylmethoxy]pyridine: A New Positron Emission Tomography Ligand for Nicotinic Receptors. J. Med. Chem. 1999, 42, 2251–2259.

Bottlaender M. et al. Biodistribution and Radiation Dosimetry of ¹⁸F-Fluoro-A-85380 in Healthy Volunteers. J. Nucl. Med. 2003, 44, 596–601.

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