Small molecules & peptides


Precursor 2 for [¹⁸F]FMAU (2'-deoxy-2'-[¹⁸F]fluoro-5-methyl-1-β-D-arabinofuranosyluracil)

2,4-Bis(trimethylsiloxy)-5-methylpyrimidine; 2,4-Bis(trimethylsilyl)-5-methyluracil; 2,4-Bis-O-(trimethylsilyl)thymine; O,O'-Bis(trimethylsilyl)thymine; Bis(O-trimethylsilyl)thymine

CA index name: Pyrimidine, 5-methyl-2,4-bis[(trimethylsilyl)oxy]-


Research Chemical


Molar mass 270.48

CAS RN [7288-28-0]

Purity ≥ 95 %

  • Colorless solid or liquid


CoA: appearance, ¹H and ¹³C NMR spectra


Mangner T.J. et al. Synthesis of 2'-deoxy-2'-[¹⁸F]fluoro-β-D-arabinofuranosyl nucleosides, [¹⁸F]FAU, [¹⁸F]FMAU, [¹⁸F]FBAU, [¹⁸F]FIAU, as potential PET agents for imaging cellular proliferation. Nucl. Med. Biol. 2003, 30, 215–224.

Buursma A.R. et al. ¹⁸F-FEAU as a radiotracer for herpes simplex virus thymidine kinase gene expression: in-vitro comparison with other PET tracers. Nucl. Med. Commun. 2006, 27, 25–30.

Alauddin M.M. et al. Direct comparison of radiolabeled probes FMAU, FHBG, and FHPG as PET imaging agents for HSV1-tk expression in a human breast cancer model. Mol. Imaging 2004, 3, 76–84.

Alauddin M.M. et al. Synthesis and evaluation of 2'-deoxy-2'-¹⁸F-fluoro-5-fluoro-1-β-D-arabinofuranosyluracil as a potential PET imaging agent for suicide gene expression. J. Nucl. Med. 2004, 45, 2063–2069

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Product No.: 2872Filling amount: 100 mg
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