Small molecules & peptides

2-O-(Trifluoromethylsulfonyl)-1,3,5-tri-O-benzoyl-α-D-ribofuranose

Precursor 1 for [¹⁸F]FEAU and [¹⁸F]FMAU (FEAU = 2'-fluoro-5-ethyl-1-β-D-arabinofuranosyluracil; FMAU = 2'-deoxy-2'-fluoro-5-methyl-1-β-D-arabinofuranosyluracil)

1,3,5-Tri-O-benzoyl-2-O-(trifluoromethanesulfonyl)-α-D-ribofuranose; (2-O-(Trifluoromethylsulfonyl)-1,3,5-tri-O-benzoyl-α-D-ribofuranose)

CA index name: α-D-Ribofuranose, 1,3,5-tribenzoate 2-(trifluoro-methanesulfonate)

Quality

Research Chemical

Characteristics

Molar mass 594.51

CAS RN [97614-41-0]

Purity ≥ 95 %

  • Colorless to off-white solid

Certificates

CoA: appearance, ¹H and ¹⁹F NMR spectra

Literature

Blasberg R.G. et al. Synthesis and Evaluation of [¹⁸F] Labeled Pyrimidine Nucleosides for Positron Emission Tomography Imaging of Herpes Simplex Virus 1 Thymidine Kinase Gene Expression. J. Med. Chem. 2006, 49, 5377–5381.

Alauddin M.M. et al. Synthesis and evaluation of 2'-deoxy-2'-¹⁸F-fluoro-5-fluoro-1-β-D-arabinofuranosyluracil as a potential PET imaging agent for suicide gene expression. J. Nucl. Med. 2004, 45, 2063–2069.

Alauddin M.M. et al. Stereospecific fluorination of 1,3,5-tri-O-benzoyl-α-D-ribofuranose-2-sulfonate esters: preparation of a versatile intermediate for synthesis of 2'-[¹⁸F]-fluoro-arabinonucleosides. J. Fluorine Chem. 2000, 106, 87–9

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Product No.Filling amountQuantity
Product No.: 2870Filling amount: 10 mg
Product No.: 2870

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