Small molecules & peptides

S-(–)-IBZM

Reference standard for S-(–)-[*I]IBZM and precursor for S-(–)-[¹²³/¹²⁵I-Tracer]IBZM

Iodobenzamide, (S)-(–)-3-Iodo-2-hydroxy-6-methoxy-N-[(1-ethyl-2-pyrrolidinyl)methyl]benzamide

CA index name: Benzamide, N-[[(2S)-1-ethyl-2-pyrrolidinyl]methyl]-2-hydroxy-3-iodo-6-methoxy-

Quality

Research Chemical

Characteristics

Molar mass 404.24

CAS RN [84226-06-2]

Purity ≥ 95 %

  • Dark yellow oil

Certificates

CoA: appearance, ¹H NMR spectrum

Literature

Kung H.F. et al. Dopamine D-2 receptor Imaging Radiopharmaceuticals: Synthesis, Radiolabeling and in Vitro binding of R(+)- and S(–)-3-iodo-2-hydroxy-6-methoxy-N-[(1-ethyl-2-pyrrolidinyl)methyl]benzamide. J. Med. Chem. 1988, 31, 1039–1043.

Cordes M. et al. Initial experience with SPECT examinations using [¹²³I]IBZM as a D2-dopamine receptor antagonist in Parkinson's disease. Eur. J. Radiol. 1991, 12, 182.

Innis R.B. et al. Amphetamine-stimulated dopamine release competes in vivo for [¹²³I]IBZM binding to the D2receptor in nonhuman primates. Synapse 1992, 10, 177.

Ichise M. et al. Iodine-123-IBZM dopamine D2receptor and technetium -99 m-HMPAO brain perfusion SPECT in the evaluation of patients with and subjects at risk for Huntington's disease J. Nucl. Med. 1993, 34, 1274.

Add to inquiry

Product No.Filling amountQuantity
Product No.: 7510Filling amount: 1 mg
Product No.: 7510Filling amount: 10 mg
Product No.: 7510

Related products

Product was added