Fludarabine precursor
Precursor for [¹⁸F]Fludarabine
Benzamide, N-benzoyl-N-[2-nitro-9-(2,3,5-tri-O-benzoyl-β-D-arabinofuranosyl)-9H-purin-6-yl]-; (2R,3S,4R,5R)-2-(6-(N-benzoylbenzamido)-2-nitro-9H-purin-9-yl)-5-(benzoyloxymethyl)tetrahydrofuran-3,4-diyl dibenzoate; [¹⁸F]Fludarabine precursor
2-Nitro-6-N,N-dibenzoyl-9-(2′,3′,5′-tri-O-benzyl-β-D-arabinofuranosyl)-9H-purine
Quality
Research Chemical
Characteristics
Molar mass 832.77
CAS RN [1169548-57-5]
Purity ≥ 95 %
- Colorless to off-white solid
- soluble in chloroform, dimethyl sulfoxide, dichloromethane
Certificates
CoA: appearance, ¹H NMR spectrum
Literature
Chantepie S. et al. ¹⁸F-Fludarabine PET for Lymphoma Imaging: First-in-Humans Study on DLBCL and CLL Patients. J. Nucl. Med. 2018, 59, 1380–1385.
Hovhannisyan N. et al. [¹⁸F]Fludarabine-PET as a promising tool for differentiating CNS lymphoma and glioblastoma: Comparative analysis with [¹⁸F]FDG in human xenograft models. Theranostics 2018, 8, 4563–4573.
Barré L. et al. [¹⁸F]-Fludarabine for Hematological Malignancies. Front. Med. 2019, 6.
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Product | Product No. | Filling amount | Quantity | ||
---|---|---|---|---|---|
/products/small-molecules-and-peptides/chemical/985e6203-093f-4abe-a50b-a81386e53203 | Precursor | Product No.: 2933 |