Small molecules & peptides

Fludarabine standard

Reference standard for [¹⁸F]Fludarabine

Adenine, 9-β-D-arabinofuranosyl-2-fluoro- (8CI); 9-β-D-Arabinofuranosyl-2-fluoro-9H-purin-6-amine; 2-Fluoro Ara-A; 2-Fluoroadenine arabinoside; 2F-Ara-A; 9-β-D-Arabinofuranosyl-2-fluoroadenine; 9-β-D-Arabinosyl-2-fluoroadenine; F-ara-A; Fludarabine; NSC 118218; NSC 118218H

2-Fluoro-9-β-D-arabinofuranosyladenine

Quality

Research Chemical

Characteristics

Molar mass 285.23

CAS RN [21679-14-1]

Purity ≥ 95 %

  • Colorless to off-white solid
  • soluble in dimethyl sulfoxide, ethanol, methanol, dimethylformamide

Certificates

CoA: appearance, ¹H and ¹⁹F NMR spectra

Literature

Chantepie S. et al. ¹⁸F-Fludarabine PET for Lymphoma Imaging: First-in-Humans Study on DLBCL and CLL Patients. J. Nucl. Med. 2018, 59, 1380–1385.

Hovhannisyan N. et al. [¹⁸F]Fludarabine-PET as a promising tool for differentiating CNS lymphoma and glioblastoma: Comparative analysis with [¹⁸F]FDG in human xenograft models. Theranostics 2018, 8, 4563–4573.

Barré L. et al. [¹⁸F]-Fludarabine for Hematological Malignancies. Front. Med. 2019, 6.

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