Small molecules & peptides


Reference standard for [¹⁸F]FMISO ([¹⁸F]fluoromisonidazole)

1-Fluoro-3-(2-nitro-imidazol-1-yl)-propan-2-ol; FMISO

CA index name: 1H-Imidazole-1-ethanol, α-(fluoromethyl)-2-nitro-


Research Chemical


Molar mass 189.14

CAS RN [13551-89-8]

Purity ≥ 95 %

  • Yellow crystals


CoA: appearance, ¹H and ¹⁹F NMR spectra


Oh S.J. et al. Fully automated synthesis of [¹⁸F]fluoromisonidazole using a conventional [¹⁸F]FDG module. Nucl. Med. Biol. 2005, 32, 899–905.

Lim J.L. et al. An efficient radiosynthesis of [¹⁸F]Fluoromisonidazole. Appl. Radiat. Isot. 1993, 44, 1085–1091.

Martin G.V. et al. Noninvasive detection of hypoxic myocardium using [¹⁸F]Fluoromisonidazole and positron emission tomography. J. Nucl. Med. 1992, 33, 2202–2208.

Rasey J.S. et al. Radiolabeled fluoromisoindazole as an imaging agent for tumor hypoxia. Int. J. Radiat. Oncol. Biol. Phys. 1989, 17, 985–991.

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