Small molecules & peptides

(+)-PHNO hydrochloride

Reference standard for [¹¹C]-(+)-PHNO

Noxazinal hydrochloride, Naxagolide hydrochloride, Nazagolide hydrochloride, Dopazinol hydrochloride, L647339, MK 458, (+)-PHNO hydrochloride, (+)-4-propyl-9-hydroxynaphthoxazine hydrochloride

CA index names: 2H-Naphtho[1,2-b]-1,4-oxazin-9-ol, 3,4,4a,5,6,10b-hexahydro-4-propyl-, hydrochloride (1:1), (4aR,10bR)-; (4aR,10bR)- 2H-Naphth[1,2-b]-1,4-oxazin-9-ol, 3,4,4a,5,6,10b-hexahydro-4-propyl-, hydrochloride, (4aR-trans)-


Research Chemical


Molar mass 283.79

CAS RN [99705-65-4]

Purity ≥ 95 %

  • Off-white solid


CoA: appearance, ¹H NMR spectrum


Wilson A.A. et al. [¹¹C]-(+)-4-Propyl-3,4,4a,5,6,10b-hexahydro-2H-naphtho[1,2-b][1,4]oxazin-9-ol as a Potential Radiotracer for in Vivo Imaging of the Dopamine D2 High-Affinity State with Positron Emission Tomography. J. Med. Chem. 2005, 48, 4153–4160.

Boileau I. et al. Decreased binding of the D3 dopamine receptor-preferring ligand [¹¹C]-(+)-PHNO in drug-naïve Parkinson's disease. Brain, 2009, 132, 1366–1375.

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