Small molecules & peptides

(+)-HNO hydrochloride

Precursor for [¹¹C]-(+)-PHNO and precursor for [¹⁸F]-(+)-F-PHNO

(4aR,10bR)- 3,4,4a,5,6,10b-hexahydro-2H-Naphth[1,2-b]-1,4-oxazin-9-ol, hydrochloride; (+)-3,4,4a,5,6,10b-Hexahydro-2H-naphtho[1,2-β][1,4]oxazin-9-ol hydrochloride; (4aR,10bR)-3,4,4a,5,6,10b-Hexahydro-2H-Naphth[1,2-β]-1,4-oxazin-9-ol, hydrochloride; (+)-HNO

CA index name: 2H-Naphtho[1,2-b]-1,4-oxazin-9-ol, 3,4,4a,5,6,10b-hexahydro-, hydrochloride (1:1), (4aR,10bR)


Research Chemical


Molar mass 241.71

CAS RN [858517-21-2]

Purity ≥ 95 %

  • Beige solid


CoA: appearance, ¹H NMR spectrum, HPLC, chiral HPLC

Product sheets (PDF)


Wilson A.A. et al. [¹¹C]-(+)-4-Propyl-3,4,4a,5,6,10b-hexahydro-2H-naphtho[1,2-b][1,4]oxazin-9-ol as a Potential Radiotracer for in Vivo Imaging of the Dopamine D2 High-Affinity State with Positron Emission Tomography. J. Med. Chem.2005, 48, 4153–4160.

Boileau I. et al. Decreased binding of the D3 dopamine receptor-preferring ligand [¹¹C]-(+)-PHNO in drug-naïve Parkinson's disease. Brain, 2009, 132, 1366–1375.

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Product No.: 1643Filling amount: 1 mg
Product No.: 1643Filling amount: 10 mg
Product No.: 1643

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