Small molecules & peptides


Precursor for [¹⁸F]FDDNP

2-(1-{6-[(2-Hydroxy)ethyl)(methyl)amino]-2-naphthyl}ethyliden)malonitrile; 2-(1,1-dicyanopropen-2-yl)-6-methyl-(2-hydroxoethyl)-amino)-naphthalene

CA index name: Propanedinitrile, [1-[6-[methyl[2-[hydroxy]ethyl]amino]-2-naphthalenyl]ethylidene]-


Research Chemical


Molar mass 291.35

CAS RN [259739-01-0]

Purity ≥ 95 %

  • Reddish solid


CoA: appearance, ¹H and ¹³C NMR spectra


Barrio J. et al. Neurofibrillary tangles (NFTs) and β-amyloid plaques (A-β) demonstrated in vivo in Alzheimer's disease (AD) patients. J. Cereb. Blood Flow Metab. 1999, 19, S2.

Adgeppa E.D. et al. Binding Characteristics of Radiofluorinated 6-Dialkylamino-2-Naphthylethylidene Derivatives as Positron Emission Tomography Imaging Probes for β-Amyloid plaques in Alzheimer's Disease. J. Neurosci. 2001, 21, RC189.

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