(S)-SDM-8 standard
Reference standard for byproduct of [¹⁸F]SDM-8 synthesis
(S)-4-(3,5-difluorophenyl)-1-((3-methylpyridin-4-yl)methyl)pyrrolidin-2-one; 2-Pyrrolidinone, 4-(3,5-difluorophenyl)-1-[(3-methyl-4-pyridinyl)methyl]-, (4S)-; (S)-SDM-8 standard; (S)-SynVesT-1 standard; (S)-MNI-1126 standard
(S)-4-(3-Fluoro-5-(fluoro)phenyl)-1-((3-methylpyridin-4-yl)methyl)pyrrolidin-2-one
Quality
Research Chemical
Characteristics
Molar mass 302.32
CAS RN [2242777-35-9]
Purity ≥ 95 %
- Colorless to off-white solid
- soluble in dimethyl sulfoxide, dichloromethane, methanol, ethyl acetate
Certificates
CoA: appearance, ¹H and ¹⁹F NMR spectra (identity), HPLC (purity), chiral HPLC (enantiomeric purity)
Literature
Li S. et al. Synthesis and in Vivo Evaluation of a Novel PET Radiotracer for Imaging of Synaptic Vesicle Glycoprotein 2A (SV2A) in Nonhuman Primates. ACS Chem. Neurosci.2019, 10, 1544–1554.
Li S. et al. ¹⁸F-SDM-8: A novel radiotracer for PET imaging of synaptic density. J. Nucl. Med.2018, 59, supplement 1, 68.
Li S. et al. First-in-human Evaluation of ¹⁸F-SDM-8, A Novel Radiotracer for PET Imaging of Synaptic Vesicle Glycoprotein 2A. J. Nucl. Med.2019, 60, supplement 1, 49.
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Product | Product No. | Filling amount | Quantity | ||
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/products/small-molecules-and-peptides/chemical/2353a515-3ce0-4091-8933-296931064532 | Reference Standard | Product No.: 3428 |