Small molecules & peptides
UCB-J precursor (GMP)
Precursor for [¹¹C]UCB-J
[¹¹C]UCB-J precursor
(R)-3-(Difluoroboranyl)-4-((2-oxo-4-(3,4,5-trifluorophenyl)pyrrolidin-1-l)methyl)-pyridin-1-ium fluoride
Quality
GMP Product
Characteristics
Molar mass 374.09
CAS RN [not yet assigned]
Purity ≥ 97 %
- colorless to off-white solid
- Tested for bioburden and bacterial endotoxins.
Certificates
CoA: appearance, ¹H and ¹⁹F NMR spectra, HPLC, chiral HPLC
Literature
Nabulsi N. et al. Synthesis and Preclinical Evaluation of ¹¹C-UCB-J as a PET Tracer for Imaging the Synaptic Vesicle Glycoprotein 2A in the Brain. J. Nucl. Med. 2016, 57, 777–784.
Mercier J. et al. Discovery of Heterocyclic Nonacetamide Synaptic Vesicle Protein 2A (SV2A) Ligands with Single-Digit Nanomolar Potency: Opening Avenues towards the First SV2A Positron Emission Tomography (PET) Ligands. Chem. Med. Chem. 2014, 9, 693–698.
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| Product | Product No. | Filling amount | Quantity | ||
|---|---|---|---|---|---|
| /products/small-molecules-and-peptides/chemical/3529d2e6-7f4a-4d9d-bcd7-39c8e99c7cf8 | Precursor | Product No.: 3421 |
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