Small molecules & peptides
HE-DPN
Reference substance for byproduct of [¹⁸F]FE-DPN synthesis
6-O-(2-hydroxyethyl)-6-O-desmethyl-diprenorphine
(5R,6R,7R,9R,13S,14S)-17-cyclopropylmethyl-4,5-epoxy-3-hydroxy-6-(2-hydroxyethoxy)-18,19-dihydro-α,α-dimethyl-6,14-ethenomorphinan-7-methanol
Quality
Research Chemical
Characteristics
Molar mass 455.59
CAS RN [not yet assigned]
Purity ≥ 95 %
- Off-white to white solid
- soluble in chloroform, dichloromethane, dimethyl sulfoxide, methanol, ethanol, acetone
Certificates
CoA: appearance, ¹H NMR spectrum
Literature
Marton, J. et al. A New Precursor for the Radiosynthesis of 6-O-(2[¹⁸F]Fluoroethyl)-6-O-Desmethyl-Diprenorphine ([¹⁸F]FE-DPN) by Nucleophilic Radiofluorination. Lett. Org. Chem. 2021, 18, 344–352.
Levinstein, M. R. et al. 6-O-(2-[18F]Fluoroethyl)-6-O-Desmethyl-Diprenorphine ([18F] FE-DPN) Preferentially Binds to Mu Opioid Receptors In Vivo. Mol. Imaging Biol. 2023, 25, 384–390.
Németh, E. et al. Optimization of a Nucleophilic Two-Step Radiosynthesis of 6-O-(2-[18F]Fluoroethyl)-6-O-Desmethyl-Diprenorphine ([18F]FE-DPN) for PET Imaging of Brain Opioid Receptors. Int. J. Mol. Sci. 2023, 24, 13152.
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| Product | Product No. | Filling amount | Quantity | ||
|---|---|---|---|---|---|
| /products/small-molecules-and-peptides/chemical/644e50a6-ada9-49cb-8ff2-4e558f211dbf | Reference Standard | Product No.: 2044 |
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