Small molecules & peptides


Reference substance for byproduct of [¹⁸F]FE-DPN synthesis




Research Chemical


Molar mass 455.59

CAS RN [not yet assigned]

Purity ≥ 95 %

  • Off-white to white solid
  • soluble in chloroform, dichloromethane, dimethyl sulfoxide, methanol, ethanol, acetone


CoA: appearance, ¹H NMR spectrum


Marton, J. et al. A New Precursor for the Radiosynthesis of 6-O-(2[¹⁸F]Fluoroethyl)-6-O-Desmethyl-Diprenorphine ([¹⁸F]FE-DPN) by Nucleophilic Radiofluorination. Lett. Org. Chem. 2021, 18, 344–352.

Levinstein, M. R. et al. 6-O-(2-[18F]Fluoroethyl)-6-O-Desmethyl-Diprenorphine ([18F] FE-DPN) Preferentially Binds to Mu Opioid Receptors In Vivo. Mol. Imaging Biol. 2023, 25, 384–390.

Németh, E. et al. Optimization of a Nucleophilic Two-Step Radiosynthesis of 6-O-(2-[18F]Fluoroethyl)-6-O-Desmethyl-Diprenorphine ([18F]FE-DPN) for PET Imaging of Brain Opioid Receptors. Int. J. Mol. Sci. 2023, 24, 13152.

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