Small molecules & peptides


Reference standard for [¹⁸F]FE-DPN


6,14-Ethenomorphinan-7-methanol, 17-(cyclopropylmethyl)-4,5-epoxy-18,19-dihydro-3-hydroxy-α,α-dimethyl-6-(2-fluoroethoxy)-, (5α, 7α)


Research Chemical


Molar mass 457.58

CAS RN [1391522-66-9]

Purity ≥ 95 %

  • Colorless to yellowish solid
  • soluble in chloroform, dichloromethane, dimethyl sulfoxide, methanol, ethanol, acetone


CoA: appearance, ¹H and ¹⁹F NMR spectra, MS (identity), HPLC (purity)


Wester H.-J. et al. Synthesis, preclinical evaluation and first human study of [¹⁸F]Diprenorphine ([¹⁸F]DPN) for central opioid receptor imaging with PET. J. Nucl. Med. 1998, 39, Proceedings of the 45th Annual Meeting, Toronto, Ontario Canada, 73P.

Wester H.-J. et al. 6-O-(2-[¹⁸F]Fluoroethyl)-6-O-Desmethyl-diprenorphine ([¹⁸F]DPN): Synthesis, Biologic Evaluation, and Comparison with [¹¹C]DPN in Humans. J. Nucl. Med. 2000, 41, 1279–1286.

Marton, J. et al. A new precursor for the radiosynthesis of 6-O-(2[¹⁸F]fluoroethyl)-6-O-desmethyl-diprenorphine ([¹⁸F]FE-DPN) by nucleophilic radiofluorination. Lett. Org. Chem. 2021, 18, 344–352.

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Product No.: 2040Filling amount: 10 mg
Product No.: 2040

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