Desmethylflumazenil
Precursor for [¹¹C]Flumazenil and precursor for 5-(2'-[¹⁸F]fluoroethyl)Flumazenil ([¹⁸F]FEF)
8-Fluoro-5,6-dihydro-6-oxo-4H-imidazo[1,5-a][1,4]benzodiazepine-3-carboxylic acid ethyl ester; Desmethyl-FMZ; Ro 15-5528
CA index name: 4H-Imidazo[1,5-a][1,4]benzodiazepine-3-carboxylic acid, 8-fluoro-5,6-dihydro-6-oxo-, ethyl ester
Quality
Research Chemical
Characteristics
Molar mass 289.26
CAS RN [79089-72-8]
Purity ≥ 95 %
- Colorless crystals
Certificates
CoA: appearance, ¹H and ¹⁹F NMR spectra
Literature
Nagren K. et al. Methylation of amide and thiol functions with [¹¹C]methyl triflate, as exemplified by [¹¹C]NMSP, [¹¹C]flumazenil and [¹¹C]methionine. J. Labelled Compd. Radiopharm. 1998, 41, 831–841.
Maziere M. et al. Synthesis of Ethyl 8-Fluoro-5,6-dihydro-5-[¹¹C]methyl-6-oxo-4H-imidazo[1,5-a][1,4]benzodiazepine-3-carboxylate (RO 15.1788–11C): A Specific Radioligand for the In Vivo Study of Central Benzodiazepine Receptors by Positron Emmission Tomography. Int. J. Appl. Radiat. Isot. 1984, 35, 973–976.
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Product | Product No. | Filling amount | Quantity | ||
---|---|---|---|---|---|
/products/small-molecules-and-peptides/chemical/7f4e0751-7d1b-42fb-97a0-acce28ea8483 | Precursor | Product No.: 1700 | Filling amount: 1 mg | ||
/products/small-molecules-and-peptides/chemical/7f4e0751-7d1b-42fb-97a0-acce28ea8483 | Precursor | Product No.: 1700 | Filling amount: 2 mg | ||
/products/small-molecules-and-peptides/chemical/7f4e0751-7d1b-42fb-97a0-acce28ea8483 | Precursor | Product No.: 1700 |