Small molecules & peptides


Precursor for [¹⁸F]Flumazenil

5,6-Dihydro-5-methyl-8-nitro-6-oxo-4H-imidazo[1,5-a][1,4]-benzodiazepine-3-carboxylic acid ethyl ester; Ro 15-2344

CA index name: 4H-Imidazo[1,5-a][1,4]benzodiazepine-3-carboxylic acid, 5,6-dihydro-5-methyl-8-nitro-6-oxo-, ethyl ester


Research Chemical


Molar mass 330.3

CAS RN [84377-97-9]

Purity ≥ 95 %

  • Yellow solid


CoA: appearance, ¹H NMR spectrum


Ryzhikov N.N. et al. Preparation of highly specific radioactivity [¹⁸F]flumazenil and its evaluation in cynomolgus monkey by positron emission tomography. Nucl. Med. Biol. 2005, 32, 109–116.

Broggini G. et al. A new synthesis of flumazenil suitable for fluorine-18 labeling. Org. Prep. Proced. Int. 2003, 35, 609–613.

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