Dopamine is one of the major neurotransmitters of the central nervous system, involved in various cerebral and peripheral physiological functions associated with neurologic and psychiatric disorders. PET imaging using the high affinity dopamine D2/3 receptor antagonist [18F]Fallypride] can provide accurate estimates of dopamine D2/3 receptor levels in the brain and has been used clinically to study receptor density and occupancy in neuropsychiatric disorders. ABX provides the precursor and reference standard for [18F]Fallypride.
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ABX advanced biochemical compounds is a global frontrunner in radiopharmaceuticals, with a focus on positron emission tomography (PET) tracers. We develop and produce all compounds and components for any kind of radiotracer – from PET and SPECT precursors, PET reagent kits and cassettes, to complete radiopharmaceutical drug production in GMP environment.
Based in Radeberg, Germany, and founded in 1997, our team of about 400 employees is specialised in custom synthesis and manufacturing of precursors and peptides according to GMP for active pharmaceutical ingredients. Thanks to our expertise combined with bleeding edge equipment, we reach highest research, production, and quality standards.
ABX is the only service provider of radiopharmaceutical production with a complete and independent supply chain – from precursor or peptide to excipients and sterile disposables.
