Small molecules & peptides

3-N-Boc-5'-O-dimethoxytrityl-3'-O-nosyl-thymidine (GMP)

Precursor for [¹⁸F]FLT (3'-deoxy-3'-[¹⁸F]fluorothymidine)

3-N-Boc-5'-O-dimethoxytrityl-3'-O-nosyl-thymidine; 3-N-Boc-1-[5-O-(4,4'-dimethoxytrityl)-3-O-nitrophenylsulfonyl-2-deoxy-β-D-lyxofuranosyl]thymidine; 1-(2'-Deoxy-3'-O-(4-nitrobenzenesulfonyl)-5'-O-(4,4'-dimethoxytrityl)-β-D-threo-pentafuranosyl)-3-(tert-butyloxycarbonyl)thymine; Boc-FLT-Precursor; Boc-FLT

CA index name: 1(2H)-Pyrimidinecarboxylic acid, 3-[2-deoxy-3-O-[(4-nitrophenyl)sulfonyl]-5-O-(triphenylmethyl)-β-D-threo-pentofuranosyl]-3,6-dihydro-5-methyl-2,6-dioxo-, 1,1-dimethylethyl ester

Quality

GMP Product

Characteristics

Molar mass 829.87

CAS RN [444717-23-1]

Purity ≥ 97 %

  • Yellowish solid

Certificates

CoA: appearance, NMR and IR spectra (identity), HPLC (purity), GC (residual solvents), Content Silver (AAS), microbiology test

Literature

Mosdzianowski C. et al. Automated FLT Synthesis Using 3-N-Boc-1-(5-O-4,4'-dimethoxytrityl)-3-O-nosyl-2-deoxy-β-D-lyxofuranosyl)-thymine as Precursor. Eur. J. Nucl. Med. 2001, 28, 1228.

Eisenhut M. et al. A new precursor for the radiosynthesis of [¹⁸F]FLT. Nucl. Med. Biol. 2002, 29, 263–273.

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Product No.: 1241Filling amount: 25 mg
Product No.: 1241Filling amount: 40 mg
Product No.: 1241

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